What does the research say about muscle mass and mortality risk?
I've been digging into some recent studies on muscle mass and its correlation with mortality. Schoenfeld and colleagues (2021) highlighted a meta-analysis showing a significant inverse relationship between skeletal muscle mass and mortality risk (effect size = 0.29). The study reviewed various populations, yet I'm curious about the specific mechanisms behind this association. Are the benefits of muscle mass purely metabolic, or do they also involve hormonal or inflammatory pathways? Anyone have insights on this from a research perspective?